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KMID : 0363420070210020089
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Journal of Korean Oriental Pediatrics
2007 Volume.21 No. 2 p.89 ~ p.96
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Effects of Sachunghwan Extract on Liver Damage in Thioacetamide Induced Rats
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Abstract
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Objectives: The purpose of this study is to examine of the effect of Sachunghwan on the liver disease.
Methods: It was induced liver damage rats by thioacetamide and dosed the extract orally and measured the activity rate of GOT, GPT, ALP and LDH.
Results:1. GOT activity was more decreased in the experimental goup than in the control goup. Group I showed continuous significance after 72 hour, Group II was significance after 96 hours. 2. GPT activity was more decreased in the experimental group than in the control group. Group I was effective after 72 hours, but group II was effective after 96 hours. 3. The significance of ALP activity in the Group I and group II was revealed after 72 hours. 4. The significance of LDH activity in the Group I and group II was revealed after 96 hours.
Conclusion:It was showded that Sachunghwan extract was effective on liver disease.
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KEYWORD
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Sachunghwan, Liver Damage, Thioacetamide
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